One Postdoc and one Ph.D. position in over-expression, biochemistry and structure of membrane transport proteins
Description Our vision is to assess the structure, supramolecular organization and dynamics of membrane transport proteins by transmission electron microscopy (TEM), atomic force microscopy (AFM) and X-ray crystallography (XRC). To this end, we clone, over-express, purify and crystallize transport proteins in 2- (2D) and 3-dimensions (3D). 2D crystals are analyzed by TEM/electron crystallography and AFM, while 3D crystals by XRC. Tasks of the successful candidates will involve cloning, over-expression and purification of pro- and eukaryotic membrane transport proteins for functional and structural studies.
Our work is part of the National Centre of Competence in Research (NCCR) TransCure From transport physiology to identification of therapeutic targets. Required qualifications The Postdoc / Ph.D. candidate should have a Ph.D. / Master degree in molecular biology or biochemistry. Experience with the over-expression in bacteria and yeast, and with the biochemistry of membrane proteins is compulsory.
Experience with transmission electron microscopy, atomic force microscopy or X-ray crystallography would be an advantage. Workplace Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Entrance Beginning of January-March 2011 or upon mutual agreement Duration of appointment 3-4 years
Application Cover letter, CV and addresses of two reference persons should be submitted by email to dimitrios.fotiadis@mci.unibe.ch
Contact
Prof. Dr. Dimitrios Fotiadis
Institute of Biochemistry and Molecular Medicine
University of Bern Bühlstrasse 28 CH-3012 Bern,
Switzerland
Email: dimitrios.fotiadis@mci.unibe.ch Useful links fotiadislab.com www.ibmm.unibe.ch www.transcure.org
Description Our vision is to assess the structure, supramolecular organization and dynamics of membrane transport proteins by transmission electron microscopy (TEM), atomic force microscopy (AFM) and X-ray crystallography (XRC). To this end, we clone, over-express, purify and crystallize transport proteins in 2- (2D) and 3-dimensions (3D). 2D crystals are analyzed by TEM/electron crystallography and AFM, while 3D crystals by XRC. Tasks of the successful candidates will involve cloning, over-expression and purification of pro- and eukaryotic membrane transport proteins for functional and structural studies.
Our work is part of the National Centre of Competence in Research (NCCR) TransCure From transport physiology to identification of therapeutic targets. Required qualifications The Postdoc / Ph.D. candidate should have a Ph.D. / Master degree in molecular biology or biochemistry. Experience with the over-expression in bacteria and yeast, and with the biochemistry of membrane proteins is compulsory.
Experience with transmission electron microscopy, atomic force microscopy or X-ray crystallography would be an advantage. Workplace Institute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland Entrance Beginning of January-March 2011 or upon mutual agreement Duration of appointment 3-4 years
Application Cover letter, CV and addresses of two reference persons should be submitted by email to dimitrios.fotiadis@mci.unibe.ch
Contact
Prof. Dr. Dimitrios Fotiadis
Institute of Biochemistry and Molecular Medicine
University of Bern Bühlstrasse 28 CH-3012 Bern,
Switzerland
Email: dimitrios.fotiadis@mci.unibe.ch Useful links fotiadislab.com www.ibmm.unibe.ch www.transcure.org
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